PHARMA KING ACE

Systematic Diagram of Purified Water System            

HVAC is an essential aspect in pharmaceutical industry as factors like temperature, relative humidity and ventilation have a direct impact on the quality of the pharmaceutical product. The designing of the HVAC should be sorted out while design concept of facility is in progress as it is linked to the architectural layouts like air locks, doorways and lobbies. Once the HVAC system is properly designed and installed it not only helps to create the required room pressure differential cascades but also prevents the cross contamination. Basically an HVAC system works by transferring the heat and moisture into and out of the air and controls the level of the air pollutant either by removing them or diluting them to a particular level. TECHNOLOGY OVERVIEW: HVAC system varies according to the size and installation capacity within a facility but the basic components remain almost the same. LAYOUT OF A TYPICAL BASIC HVAC SYSTEM HEATING SYSTEM: The heat source is either a furnace or ...

Vacancy at zee Laborate limited

TYPES OF GRANULATION Granulation can be achieved by three method as follows :- 1. Direct compression          Crystalline substance like sodium chloride, sodium bromide may be compressed directly. The vast majority of medicinal agents are rarely so easy to tablet, direct compression material should posses good flow and compresibility and must be inert, tasteless, able to disintegrate and inexpensive. Method (Drug + filler + disintegrant + lubricant + glidant ) all are blend directly after sifting through Viber sifter and compressed 2. Dry Granulation    It is used in situations where effective dose of a drug is too high for direct compaction and the drug is sensitive to heat, moisture, or both which preclude wet granulation. This is also called slugging method. Method A.      (Drug + filler + lubricant) All are.       blend then precompression done and     after that   comminu...

THIN LAYER CHROMATOGRAPHY Introduction Thin layer chromatography (TLC) is a technique in which a solute undergoes distribution between two phases, a stationary phase, acting through adsorption and a mobile phase in the form of liquid. The adsorbent is relatively thin, uniform layer of dry, finely powdered material applied to glass, plastic or metal sheet. Glass plates are most commonly used. Separation may also be achieved on the basis of partition or a combination of partition and adsorption, depending on a particular type of support, its preparation and its use with different solvent. Identification can be effected by observation of spots of identical Rf value and about equal magnitude obtained respectively, with an unknown and reference sample chromatograph on the same plate. Apparatus required Flat  glass plates of appropriate dimensions. b)  An aligning tray or plate surface on which the plates can be aligned and        ...

POLARIMETRY Introduction The electric fields associated with the beam of monochromatic light, vibrate in all directions perpendicular to the directions of propagation of light. Certain crystalline materials have different refractive indices for light, whose field vibrates parallel or perpendicular to the principal plane of the crystal. As a result, a Nicol prism constructed of this material transmits only light whose electric field oscillates in one plane. Optical activity concerns with the interaction of such plane polarised light with certain materials, particularly solutions of some organic compounds. When a plane polarised light passes through a medium, it is retarded to an extent indicated by the refractive index of the medium. When the later is optically inactive, both circularly polarised components are retarded to the same extent and the beam emerges from the medium, polarised in the same plane as the incident beam. If the medium is optically active, the components are re...

Vacancy at Corona Remedies pvt ltd For various posts

Material  Starch  Preservative  - sodium methyl paraben, sodium propyl paraben etc. Binder - PVPK 30/40/60 , sugar,  gelatin etc. Sufactant - sodium Lauryl sulphate etc.  5. Base - Purified Water Procedure       1. Take purified water in paste kettle and add surfactant and preservatives to it now      2. Heat the purified water to 100°C till boil      3. Dissolve starch in purified water in separate vessel and stirr till traslucent mass obtained     4. Add this translucent mass to hot purified water in paste kettle and stirr till it become slightly yellowish

Indian pharmaceutical  GMP guidelines  are given in Drugs & Cosmetics Act 1940. Rules are given for pharmaceuticals and schedules are there to comply those rules. MINISTRY OF HEALTH AND FAMILY WELFARE (Department of Health) updates this time to time. Pharmaceutical industries in India those are manufacturing the drug products for domestic market have to follow the Drugs & Cosmetics Act. It contains 168 rules from 1 to 168 and 25 Schedules from Schedule A to Schedule Y . Different type of forms are also given for different type of approvals from drug authorities. Following are the schedules: Schedule A:  Forms and applications Schedule B :  Fees for test or analysis by the Central Drugs Laboratories or State Drugs Laboratories Schedule C :   Biological and Special Products Schedule C(1):  Other Special Products Schedule D:  Class of Drugs: Extent and conditions of exemption Schedule D(I):...

Formulation and manufacturing of Lipstick Lipstick:- Lipstick  is a cosmetic product  containing pigments , oils , waxes , and emollients  that apply color, texture, and protection to the lips . Lipstick Raw Materials  Before making lipstick, ingredients must be chosen. The primary ingredients of every lipstick are waxes, oils, and pigments, but many other substances can be introduced into the mix that will enhance certain parts of the final product and add it some specific new features such as fragrance, longevity and gloss. The wax used usually involves some combination of three types : beeswax, candelilla wax or the more expensive carnauba. Wax enables the mixture to be formed into the easily recognized shape of the cosmetic. Oils such as mineral, caster, lanolin, or vegetable are added to the wax. Some of the most common secondary ingredients are preservatives (to ensure longer shelf life), alcohol (solvent for other substances), fragrance (oils and waxe...