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Procedure for Calibration of Balances in pharmaceutical industry

  MONTHLY CALIBRATION OF BALANCES  For monthly Calibration of Balances check following parameters- 1. Accuracy - verify the balance with minimum weight (least count × 100), 5%, 20%, 50%, 90% capacity of respective balance capacity. Tolerance - the variation if any should be ± least count of the balance or ± 0.2% of certified standard weight used whichever is higher    2. Reproducibility -  Check the reproducibility by using minimum standard weight of balance capacity. Place the weight in the middle of the weighing pan observe the displayed value  Then calculate the %RSD by following formula  RSD= SD×100 / X  Where,  X= mean of the individual value Acceptance = %RSD should not be more than 2.0% 3. Eccentricity  Eccentricity is the difference between the weight placed in centre and at peripheral points of the weighing pan