Following parameters checked during granulation process 1. Angle of repose- Angle of repose of any solid in pulverized form represent an angle measured in theta, Angle of repose = tan-¹(2h/d), unit is degree (°) Acceptance = < 25° = Excellent 25°-30°= Good 30°-40°= Average >40°= Bad 2. LOD ( Loss on Drying ) Test is designed to measure the amount of water and volatile matters in a sample when the sample is dried under specified conditions eg. 100° C for 5 minutes Formula LOD = Initial weight before drying - final weight after drying / initial weight before drying ×100 3. Compressibility index Measure of the propensity of a powder to be Compressed also known as Carr's index Formula Carr's index = true density - bulk density / bulk density ×100 Acceptance <15% = Good flow >25% = Poor flow 15%- 25% = Smooth for compression 4. Bulk density and tap density Bulk densit...
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