PHARMA KING ACE

  Introduction In pharmaceutical manufacturing, line clearance is one of the most critical GMP (Good Manufacturing Practice) activities. It ensures that no leftover materials, labels, or documents from the previous batch remain before starting a new batch. Effective line clearance prevents mix-ups, contamination, and regulatory non-compliance, making it a key step in ensuring patient safety and product quality. What is Line Clearance? Line Clearance is the systematic process of verifying that: The manufacturing or packaging area is free from previous batch materials Equipment is cleaned and ready for the next operation Documents and labels belong to the current batch 👉 In simple words: Line Clearance = Cleaning + Checking + Clearing (3C) The 3C Concept of Line Clearance 1️⃣ Clearing of Line This involves removing all materials from the previous batch, such as: Leftover labels Polybags and cartons Rejected tablets or capsules Batch documents 2️⃣ Cleaning of Line Cleaning ensures no...